- Nephrotoxicity (kidney damage) is a major concern. The dose is reduced when the patient's creatinine clearance (a measure of renal function) is reduced. Adequate hydration and diuresis is used to prevent renal damage...Nephrotoxicity is a dose-limiting side effect.
- Neurotoxicity (nerve damage) can be anticipated by performing nerve conduction studies before and after treatment.
- Nausea and vomiting: cisplatin is one of the most emetogenic chemotherapy agents, but this symptom is managed with prophylactic antiemetics in combination with corticosteroids.
- Ototoxicity (hearing loss): unfortunately there is at present no effective treatment to prevent this side effect, which may be severe.
- Electrolyte disturbance: Cisplatin can cause hypomagnesaemia [magnesium], hypokalaemia [potassium] and hypocalcaemia [calcium].
- Myelotoxicity: This agent can also cause profound bone marrow suppression.
My magnesium & calcium counts are high, and my kidney function is very good, and I haven't had any of the other side effects from the chemo except nausea. My blood counts (white blood cells etc) have gone down a lot but are still within healthy range. I think I said somewhere that my dosage of the chemotherapy drug is low - he said today that it isn't low. It's the maximum dosage for when it's combined with radiation. (When it's not combined, it's a higher dosage given less often.)
He also gave me a prescription for vicodin, which is delightful. I forgot to say about the HDR treatment that they (necessarily) punctured my bladder. Also, after the treatment is over, especially if the tumor is eliminated, I may end up with a tumor-sized hole inside me. Hopefully, it will heal on its own, but could take several months. These ideas don't bother me nearly as much as they did the first time I heard them.
Another thing we talked about is the post-treatment timeline. I guess I had this idea that on date x, I would know what my situation is. But it doesn't seem to work like that. After a month I get a CT scan, after 3 months I get a PET scan. Then there will be a lot more info...but still it all seems somewhat...provisional. It's a See What Happens kind of situation...
What the heck am I supposed to do with the hat I've been knitting? :)
ReplyDeleteI'm sending love and best wishes and soon a care package!
Love!
Hats still useful!! x
ReplyDeleteLuckily we also get to discuss my anus and my bladder quite a bit too.
ReplyDelete